Mafia 3: My Name's Lincoln Clay... (killing Santangelo)
This task becomes available after you complete the mission "Kill Uncle Lou Marcano", where you catch and eliminate Lou. From a cutscene you will learn that Sal Marcano has paid for the services of the elite hitman Santangelo and this enemy will actively search for you in the French Ward district. BEFORE you attempt to enter the district, make sure that Lincoln has a full supply of adrenaline injections, a bullet-proof vest, grenades and good firearms (e.g. a rifle or a machinegun).

The confrontation with Santangelo will be similar to skirmishes with other hitmen, with whom Lincoln had to deal with in the earlier stages of the game. The elite assassin cannot be found in any specific location in the French Ward district. Instead, he and his gangsters will track down and attack Lincoln soon after the main character will reach the previously mentioned part of the city.

Right after you find yourself in Santangelo's crosshairs it would be best to fall back to a more defensible position, to make it easier for you to win the battle. It is best to retreat to the vicinity of one of the rackets, which Lincoln has previously taken over, the friendly personnel will then aid you in your fight. If you have no other choice, retreat into one of the side alleyways, which will make it harder to surround Lincoln.
Hide behind solid cover and do not hold back when it comes to unleashing your arsenal of weaponry, as Santangelo will be accompanied by a quite sizeable group of well-equipped gangsters. Do not let the enemies to draw too near to you and change cover if you see that they are about to use explosives. Santangelo is a more resilient enemy, but throwing several explosives his way, or firing at him with a good firearm will deprive him of hit points quite quickly. After you have won the battle (make sure that all of Santangelo's goons are dead!) approach Santangelo to finish him off (by holding the interact button).
- Mafia III Game Guide
- Mafia 3: Game Guide
- Mafia 3: Story missions
- Mafia 3: Prologue (missions 1-9)
- Mafia 3: Old Times' Sake (recruitment of Cassandra)
- Mafia 3: Prostitution (prostitution racket)
- Mafia 3: Smack (heroin racket)
- Mafia 3: Kill Ritchie Doucet
- Mafia 3: Cut and Run (recruitment of Burke)
- Mafia 3: Moonshine (moonshine racket)
- Mafia 3: Protection (paid protection racket)
- Mafia 3: Kill the Butcher
- Mafia 3: We Partners Now? (recruitment of Vito)
- Mafia 3: Union Extortion (extortion racket)
- Mafia 3: Contraband (contraband racket)
- Mafia 3: Get Michael Grecco (kidnapping Grecco)
- Mafia 3: An Emotional Attachment (meeting with underbosses)
- Mafia 3: Garbage (illegal garbage disposal racket)
- Mafia 3: Guns (weapons racket)
- Mafia 3: Get Enzo Conti (encounter with Enzo Conti)
- Mafia 3: Construction (construction racket)
- Mafia 3: Blackmail (blackmail racket)
- Mafia 3: Kill Tony Derazio (murdering Tony Derazio)
- Mafia 3: Auto Theft (car stealing racket)
- Mafia 3: Smuggling (smuggling racket)
- Mafia 3: Kill Frank Pagani Setup (preparations for the murder)
- Mafia 3: Kill Frank Pagani Takedown (murdering Frank Pagani)
- Mafia 3: PCP (drugs racket)
- Mafia 3: Southern Union (racist organization racket)
- Mafia 3: Kill Remy Duvall (murdering Remy Duvall)
- Mafia 3: Kill Olivia Marcano (eliminating Olivia Marcano)
- Mafia 3: Sex (prostitution racket)
- Mafia 3: Drugs (drugs racket)
- Mafia 3: Kill the Judge (murdering Judge Holden)
- Mafia 3: Kill "Uncle" Lou Marcano (murdering Lou Marcano)
- Mafia 3: My Name's Lincoln Clay... (killing Santangelo)
- Mafia 3: Gambling (illegal gambling racket)
- Mafia 3: Black Market (black market goods racket)
- Mafia 3: Rescue Alvarez
- Mafia 3: Kill Tommy Marcano (murdering Tommy Marcano)
- Mafia 3: Preparations for the final story mission
- Mafia 3: Kill Sal Marcano (murdering Sal Marcano) - final mission
- Mafia 3: Mafia 3 endings
- Mafia 3: Story missions
- Mafia 3: Game Guide
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